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本文报告首例由于多毛细胞肝浸润引起的暴发性肝炎。病例报告患者43岁,女性。1987年曾诊断为典型的多毛细胞白血病。1988年11月患者因面颈部蜘蛛痣,肝掌和弥漫性毛细管扩张而就诊。当时肝跨距正常。实验室检查:门冬氨酸转氨酶(AST)56u/L(正常12～31u/L);碱性磷酸酶(AKP)283u/L(正常76～196u/L);γ-谷氨酰转移酶(γ-GT)157u/L(正常6～35u/L);总胆红素10pmol/L(正常≤19umol/L);超声波检查提示肝正常、脾肿大。肝活检证实有少量多毛细胞浸润及含铁血黄素沉着,而肝细胞无损害。
This article reports the first case of fulminant hepatitis due to hairy liver infiltrates. Case Report Patient 43 years old, female. 1987 was diagnosed as typical hairy cell leukemia. November 1988 patients due to face and neck spider nevus, liver palms and diffuse capillary dilation and treatment. Liver span was normal at that time. Laboratory tests: aspartate aminotransferase (AST) 56u / L (normal 12 ~ 31u / L); alkaline phosphatase (AKP) 283u / L (normal 76 ~ 196u / L); γ-glutamyl transferase (γ-GT) 157u / L (normal 6 ~ 35u / L); total bilirubin 10 pmol / L (normal ≤ 19umol / L); ultrasound examination showed normal liver and splenomegaly. Liver biopsy confirmed a small amount of hair cells infiltration and hemosiderin deposition, and liver cells without damage.