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目的:为脂蛋白肾病的治疗提供参考,同时探讨临床药师在整个治疗过程中发挥的作用。方法:对1例脂蛋白肾病患者所采用的3种不同治疗方案(包括免疫抑制疗法、双重血浆滤过、降脂降尿蛋白护肾疗法)进行疗效评价,临床药师协助医师制定治疗方案、通过药学监护提供用药调整建议、借助随访进行患者教育及预后分析。结果:1免疫抑制疗法对患者病情无效;2双重血浆滤过起效快,但费用高、易复发;3降脂降尿蛋白护肾疗法疗效较好、相对安全、经济,且维持较长时间不复发。结论:降脂降尿蛋白护肾疗法最适合该患者的病情,临床药师协助医师,保证患者在可耐受不良反应的前提下获得最大治疗效果,在整个治疗过程中发挥了重要作用。
Objective: To provide a reference for the treatment of lipoprotein nephropathy, and to explore the role of clinical pharmacists in the entire course of treatment. Methods: The efficacy of three different treatment regimens (including immunosuppressive therapy, dual plasma filtration, blood-fat reducing proteinuria and renal protection therapy) in one patient with lipoprotein nephropathy was evaluated. The clinical pharmacist assisted the physician in formulating the treatment plan Pharmacokinetic advice to provide medication adjustment, follow-up with patient education and prognosis analysis. Results: 1 immunosuppressive therapy in patients with disease invalid; 2 double plasma filtration quick onset, but the high cost, easy to relapse; 3 lipid-lowering proteinuria Kidney therapy is better, relatively safe, economical, and maintain a long time Do not relapse. CONCLUSION: The therapy of lowering blood fat and reducing urine protein in kidney protection is the most suitable for this patient’s condition. The clinical pharmacist assists the physician to ensure that the patients get the maximal therapeutic effect under the premise of being tolerant to adverse reactions and plays an important role in the whole treatment process.