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目的评价粪便转铁蛋白检测对上消化道肿瘤的筛检作用。方法采用单克隆血红蛋白检测法和粪便转铁蛋白检测法对40例经胃镜确诊的上消化道肿瘤患者进行粪便潜血检测,比较两者阳性率差异及其与胃镜结果的符合率。结果所检40例标本中,单克隆血红蛋白法阳性率20%,粪便转铁蛋白法阳性率82.5%,差异有显著意义(P<0.01)。结论粪便转铁蛋白检测对上消化道肿瘤性出血敏感性高于单克隆血红蛋白法,适用于上消化道肿瘤的过筛检验。
Objective To evaluate the screening effect of fecal transferrin on upper gastrointestinal tumors. Methods Monoclonal hemoglobin assay and fecal transferrin assay were used to detect fecal occult blood in 40 patients diagnosed as upper gastrointestinal cancer by gastroscope. The positive rates of the two methods were compared with those of gastroscopy. Results The positive rate of monoclonal antibody hemoglobin was 20% and the positive rate of transferrin of faecal was 82.5% in 40 samples, the difference was significant (P <0.01). Conclusion The detection of fecal transferrin is more sensitive to hemorrhage of upper gastrointestinal tract than to monoclonal hemoglobin method and is suitable for the screening of upper gastrointestinal tumors.