肾上腺髓质素是一种各种器官分泌的多效性的舒血管多肽。肾上腺髓质素的产生首先是一种蛋白前体,然后裂解成成熟的肾上腺髓质素和中期的质素。而后者水平与与脓毒症的严重程度相关并有预后价值。肾上腺素髓质素对血管张力具有平衡的作用。在上一期的重症监护杂志中,在机械通气小鼠肺炎球菌性肺炎模型中,外源性肾 Adrenomedullin is a pleiotropic pleiotropic polypeptide secreted by various organs. Adrenomedullin production is primarily a protein precursor, which is then cleaved into mature adrenomedullin and mid-quality. The latter level correlates with the severity of sepsis and has prognostic value. Adrenomedullin has a balanced effect on vascular tone. In the last issue of Critical Care Medicine, in a mechanically ventilated mouse pneumococcal pneumonia model, exogenous kidneys