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细胞周期G_2期延迟与调控细胞周期的特定蛋白──细胞周期素(Cyclin)有关,辐射作用后,细胞周期素的转录、表达发生改变,与细胞周期素结合的p34~(cdc2)磷酸化和脱磷酸化状态也发生变化,从而导致细胞在G_2期滞留。
The cell cycle G 2 phase delay is related to the regulation of the cell cycle specific protein ── Cyclin. After radiation, the transcription and expression of cyclin are changed. The phosphorylation of cyclin-binding p34 ~ (cdc2) The status of dephosphorylation also changed, which resulted in the cells staying in G2 phase.