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目的探讨早发型重度子痫前期(EOSP)终止妊娠的临床效果。方法选取2010年8月-2013年1月在我院进行治疗的EOSP孕妇124例,随机分为观察组和对照组,观察组进行积极终止妊娠干预治疗,对照组给予保守治疗,比较两组治疗效果。结果观察组孕产妇心功能不全发生率为16.13%,肾功损害发生率为20.97%,肝功损害发生率为43.55%;对照组孕产妇心功能不全发生率为1.61%,肾功损害发生率为3.23%,肝功损害发生率为17.74%,组间差异有统计学意义(P<0.05);观察组新生儿预后显著差于对照组(P<0.05)。结论保守治疗的基础上,必要时终止妊娠,可改善早发型重度子痫妊娠预后。
Objective To investigate the clinical effect of termination of early-onset severe preeclampsia (EOSP). Methods 124 pregnant women with EOSP who were treated in our hospital from August 2010 to January 2013 were randomly divided into observation group and control group. The observation group was treated with active termination of pregnancy intervention and the control group received conservative treatment. The two groups were compared effect. Results The incidence of heart failure in the observation group was 16.13%, the incidence of renal damage was 20.97% and the incidence of liver damage was 43.55%. The incidence of heart failure in control group was 1.61%, the incidence of renal damage The incidence of liver damage was 17.74%. The difference between the two groups was statistically significant (P <0.05). The prognosis of neonates in the observation group was significantly lower than that in the control group (P <0.05). Conclusions On the basis of conservative treatment, if necessary, termination of pregnancy can improve the prognosis of early-onset severe eclampsia.