不稳定型心绞痛的处理仍是临床难题,其心肌缺血的发病机制可能是氧供应减少,而非氧需量增加.因此是否应该使用β-肾上腺能受体阻滞剂仍属疑问,后者对冠状动脉痉挛患者是有害的.硝酸酯能降低心肌氧需量,增加氧供应,因而广泛地用于治疗不稳定型心绞痛,但某些患者单用硝酸酯无效,而且长程治疗往往有不良反应.钙通道阻滞剂有若干对静息性或劳力性心绞痛患者可能有益的药理学特性,能直接地通过阻滞钙离子进入血管平滑肌或间接地通过对交感神经的影响而扩张体循环血管,从而减少心肌在任何作功水 The treatment of unstable angina pectoris is still a clinical problem, the pathogenesis of myocardial ischemia may be decreased oxygen supply, rather than an increase in oxygen demand.Therefore, it should be questioned whether to use β-adrenergic receptor blockers, the latter Is harmful to patients with coronary artery spasm Nitrate reduces myocardial oxygen demand and increases oxygen supply and is therefore widely used in the treatment of unstable angina, but some patients are ineffective with nitrates alone, and long-range therapy often has adverse effects Calcium channel blockers have several pharmacological properties that may be beneficial to patients with rest or angina pectoris and can directly expand the systemic circulation of blood vessels by blocking the entry of calcium ions into the vascular smooth muscle or indirectly by acting on the sympathetic nerve Reduce myocardial water at any work