本文报道了孕早期用胎儿镜在超声指导下,经宫颈绒毛活检获得绒毛标本,并对其进行DNA分析,产前确定胎儿性别的新方法。随着分子遗传学的发展,已有可能用染色体特异性探针在分子水平上进行核型分析.分子杂交法已证明,男胎Y染色体有特异的DNA顺序.它位于Y染色体长臂远侧的异染色质区,经放射性探针杂交后,作放射自显影检查,可出现一明显的深带(3.4kb),此即Y This article reports the first trimester pregnancy under the guidance of ultrasound in villi biopsy obtained by villus specimens, and its DNA analysis of prenatal fetal sex to determine a new method. With the development of molecular genetics, it has been possible to perform karyotyping at the molecular level using chromosome-specific probes, which have been shown to have a specific DNA sequence on the Y chromosome of the male fetus, located on the far side of the long arm of the Y chromosome Of heterochromatin region, after hybridization by radioactive probes, autoradiography examination, there may be a clear deep band (3.4kb), which is Y