婴幼儿正处于生长发育的特殊阶段,对许多药物很敏感。他们的肝、肾功能及血脑屏障不健全,在肝内起主要解毒作用的葡萄糖醛酸转移酶的活性很低,代谢药物能力差,加上肾功能尚未成熟,稍不留意就会产生不良反应。目前国内药物的生产厂家在药品使用说明书中,对婴幼儿用药的指导及副作用方面缺乏详尽的介绍,因此本文就婴幼儿用药方面应注意的事项阐述如下。 Infants and young children are at a special stage of growth and development, and are sensitive to many drugs. Their liver, kidney function and blood-brain barrier is not perfect, the main detoxification in the liver glucuronosyltransferase activity is low, poor metabolism of drugs, coupled with renal function is not yet mature, a little careless will have a bad reaction. At present, domestic manufacturers of drugs in the drug manual, the guidance of infant medication and the lack of detailed description of side effects, this article on infant medication should be noted as follows.