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目的:分析对照奥曲肽与垂体后叶素治疗肝硬化患者食道静脉曲张破裂出血的临床效果。方法:治疗组50例在综合性治疗措施基础上,给予奥曲肽0.1mg加10%葡萄糖溶液30ml静脉注射,然后用0.5mg奥曲肽置0.9%生理盐水1000ml中静脉滴注16小时;对照组40例在综合性治疗措施(与治疗组相同)后,给予垂体后叶素200U加入0.9%生理盐水500ml,按0.2~0.4U·ml~(-1)·分~(-1)持续静脉滴注16小时。结果:治疗组止血总有效率为92%,对照组的止血总有效率为65%,两组结果差异显著(P<0.05)。结论:奥曲肽是一种止血效果好、副反应少、使用方便的止血药物。
OBJECTIVE: To analyze the clinical effect of octreotide versus pituitrin in the treatment of esophageal variceal bleeding in cirrhotic patients. Methods: 50 cases of the treatment group were given intravenous injection of octreotide 0.1mg and 10% glucose solution 30ml on the basis of comprehensive treatment measures, and then intravenously dripped 0.5mg octreotide in 1000ml of 0.9% saline for 16 hours. In control group 40 cases After the comprehensive treatment (the same as the treatment group), 200U of vasopressin was given to 500ml of 0.9% saline and the infusion of 0.2 ~ 0.4U · ml ~ (-1) · min ~ (-1) was continued for 16 hours . Results: The total effective rate of hemostasis was 92% in treatment group and 65% in control group. There was significant difference between the two groups (P <0.05). Conclusion: Octreotide is a hemostatic effect, side effects, easy to use hemostatic drugs.