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目的:探讨自拟中药汤剂联合西药治疗紧张型头痛疗效分析及不良反应观察,为临床诊断治疗提供参考。方法:将本组500例紧张型头痛患者按照随机数字表法将其随机分为对照组(n=250)和观察组(n=250);对照组给予盐酸阿米替林片治疗,治疗组在对照组治疗基础上服用中药自拟汤剂;两组治疗均以3周为1个疗程。结果:治疗组治疗后总有效率(95.20%)显著高于对照组(70.80%),且有显著性差异(P<0.05);治疗组轻度疼痛患者显著多于对照组,且有显著性差异(P<0.05);治疗组中度疼痛和重度疼痛均显著少于对照组,且有显著性差异(P<0.05);两组患者均无明显不良反应发生。结论:自拟中药汤剂联合西药治疗紧张型头痛疗效显著,且无明显不良反应发生,具有重要的临床研究价值,值得推广。
Objective: To investigate the curative effect and adverse reactions of self-made traditional Chinese medicine decoction combined with western medicine in the treatment of tension-type headache, and to provide reference for clinical diagnosis and treatment. Methods: 500 patients with tension-type headache were randomly divided into control group (n = 250) and observation group (n = 250) according to random number table. The control group was treated with amitriptyline hydrochloride and the treatment group In the control group based on the treatment of traditional Chinese medicine self-decoction; two treatment were 3 weeks for a course of treatment. Results: The total effective rate (95.20%) in the treatment group was significantly higher than that in the control group (70.80%), and there was a significant difference (P <0.05). The treatment group had more mild pain than the control group (P <0.05). The moderate pain and severe pain in the treatment group were significantly less than those in the control group (P <0.05). No adverse reactions occurred in both groups. Conclusion: Self-made traditional Chinese medicine decoction combined with western medicine treatment of tension-type headache significant effect, and no obvious adverse reactions, has important clinical research value, it is worth promoting.