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应用外源性肺表面活性物质治疗早产儿严重肺透明膜病１０例，均取得以好的效果。药液（２００ｍｇ／ｋｇ）通过气管插管及导骨分４次注入气管内，并通过正压通气使之均匀分布于两肺气道。为确保安全、有效，注药前必须保持气管插管及导管的良好位置，并吸清痰液。用药后６小时内不作气管内吸引。持续监测生命体征，早期发现和处理可能发生的不良反应，并及时调整呼吸机参数以避免氧中毒和气压伤。
The application of exogenous pulmonary surfactant in the treatment of severe hyaline membrane disease in 10 preterm infants, have achieved good results. The medicinal solution (200mg / kg) is injected into the trachea 4 times through the endotracheal tube and the guide bone, and evenly distributed in both lung airways by positive pressure ventilation. In order to ensure safety and effectiveness, we must maintain a good position of tracheal intubation and catheter and suction sputum before injection. No intratracheal attraction within 6 hours after treatment. Continuously monitor vital signs, early detection and treatment of possible adverse reactions, and timely adjustment of ventilator parameters to avoid oxygen poisoning and barotrauma.