We used the maps of urban land-use in 1978, 1991, 1994, 2000 and 2004, and softwares such as ArcGIS, Fragstats to analyze the spatio-temporal process of urban residential space quantitatively. Some methods, such as di- rection analysis and landscape pattern analysis, were employed. The results show that: 1) the residential land grew very rapidly in Hefei from 1978 to 2004, and the increased land was distributed mainly in the central city zone surrounded by a moat; however, after 1994, it was distributed mainly outside the 1th Ring Road; 2) the expansion speeds were very different in different directions: there exists a fastest expansion of residential land in the directions of NE-NNE, SW and SSE, and a slowest one in the directions of E and SEE; 3) the residential land growth went through four stages: slow circular expansion in 1978-1991, ’axes + fan wings’ expansion in 1991-1994, more rapid circular expansion in 1994-2000 and ’fan-wings’ expansion in 2000-2004; 4) the expansion intensity was also different in all directions in the period of 1978 to 1994, and the most was in SW and then NW; and 5) there were more and more residential land area, and the spatial agglomeration was improved increasingly. We used the maps of urban land-use in 1978, 1991, 1994, 2000 and 2004, and softwares such as ArcGIS, Fragstats to analyze the spatio-temporal process of urban residential space quantitatively. Some methods, such as di- rection analysis and landscape pattern analysis, were employed. The results show that: 1) the residential land grew very rapidly in Hefei from 1978 to 2004, and the increased land was distributed mainly in the central city zone surrounded by a moat; however, after 1994, it was distributed mainly outside the 1th Ring Road; 2) the expansion speeds were very different in different directions: there exists a fastest expansion of residential land in the directions of NE-NNE, SW and SSE, and a slowest one in the directions of E and SEE; 3) the residential land growth went through four stages: slow circular expansion in 1978-1991, ’axes + fan wings’ expansion in 1991-1994, more rapid circular expansion in 1994-2000 and ’fan-wings’ expansion in 2000-2004; 4) the expansion intens ity was also different in all directions in the period of 1978 to 1994, and the most was in SW and then NW; and 5) there were more and more residential land area, and the spatial agglomeration was improved increasingly.