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为了观察蕈样霉菌病患者内脏与深部淋巴结侵犯情况,给治疗提供依据,作者等观察了13例经皮肤活检证实的蕈样霉菌病患者的内脏改变,对肝、脾、淋巴结进行了病理研究,部分材料作了电镜观察。剖腹术前曾进行末梢血涂片检查,寻找异常细胞。13例中4例有一个或多个器官受侵,其中3例皮肤病变属肿瘤期,1例属红斑期。4例脾脏、3例腹部淋巴结和1例肝脏受侵,在切除的13例脾中,有病变的4例重250～480克(未被累及者重65～155克)。其中1例肉眼可见肿瘤结节。镜下
In order to observe the involvement of visceral and deep lymph nodes in patients with mycosis fungoides and provide evidence for treatment, the authors observed changes in viscera in 13 patients with mycosis fungoides confirmed by skin biopsy, and performed pathological studies on the liver, spleen, and lymph nodes. Some materials were observed by electron microscopy. Before the laparotomy, a peripheral blood smear was performed to look for abnormal cells. Of the 13 cases, one or more organs were invaded in 4 cases, of which 3 were skin lesions and 1 was erythema. 4 cases of spleen, 3 cases of abdominal lymph nodes, and 1 case of liver invasion. Of the 13 cases of spleen removed, 4 cases of lesions weighed 250-480 grams (65-155 grams without being involved). One of these tumors was visible to the naked eye. Under the microscope