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对29例糖尿病人行基础状态血生长激素(GH)测定,其中9例升高。此9例中7例有慢性并发症,而20例GH正常者仅4例有慢性并发症(P<0.05)。对9例血GH升高者行阿托品试验(1mg静注),结果表明:注射阿托品后30′血GH即见下降,40′、60′、75′各时相GH仍保持下降趋势,至90′下降最明显,与0′时相比较有显著差异(P<0.05)。试验前后血糖值无明显变化。本试验表明:阿托品具有抑制糖尿病高GH血症的作用,这可能有助于糖尿病慢性并发症,尤其是血管并发症的防治,值得临床进一步观察。
29 cases of diabetic patients underwent basic status of blood growth hormone (GH) determination, of which 9 cases increased. Seven of the nine patients had chronic complications, while only four of the 20 patients with GH normal had chronic complications (P <0.05). Atropine test (1 mg intravenous injection) was performed on 9 cases of hyperglycemia. The results showed that the blood GH decreased at 30 ’after injection of atropine, while the GH decreased at 40’, 60 ’and 75’ ’The most significant decline, compared with 0’ when there was significant difference (P <0.05). No significant changes in blood glucose before and after the test. This study shows that: atropine has the effect of inhibiting hyperlipidemia in diabetes, which may contribute to chronic complications of diabetes, especially the prevention and treatment of vascular complications, it is worth further clinical observation.