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对牙周健康者和龈炎、牙周炎患者２５人共１３０个牙位的龈沟液（ＧＣＦ）中硷性磷酸酶（ＡＬＰ）活性进行了检测。ＧＣＰ－ＡＬＰ活性（ｕ／ｕＬ或ｕ／牙）在炎症牙位和健康牙位间有显著差别，与牙龈指数（ＧＩ）和附着丧失（ＡＬ）呈正相关性。炎症牙位经牙周综合治疗６周后，其ＧＣＦ－ＡＬＰ活性显著降低。说明ＧＣＰ－ＡＬＰ水平能反映出牙周组织炎症的进展情况。
The alkaline phosphatase (ALP) activity in gingival crevicular fluid (GCF) with a total of 130 teeth from 25 healthy persons with periodontal disease and gingivitis and periodontitis was tested. There was a significant difference in GCP-ALP activity (u / uL or u / tooth) between inflammatory and healthy teeth with a positive correlation with gingival index (GI) and attachment loss (AL). After 6 weeks of periodontal comprehensive treatment, the GCF-ALP activity of inflammatory tooth was significantly decreased. GCP-ALP level can reflect the progress of periodontal inflammation.