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用流式细胞仪检测结果提示,Graves氏病患者在急性期外周血中CD、CD细胞数无变化(P>0.05);CD细胞明显下降(P<0.01),CD4/CD8比值明显升高(P<0.01)。缓解期患者CD、CD、CD细胞数及CD4/CD8比值均无明显变化(P>0.05)。用化学比色法定量测定患者中性粒细胞吞噬功能。与正常对照组相比,Graves氏病患者的中性粒细胞吞噬功能有明显下降(P<0.01)。这些指标对Graves氏病病因机制的探讨及治疗后预后观察具有一定的帮助。
The result of flow cytometry showed that the number of CD and CD cells in peripheral blood of patients with Graves’ disease did not change (P> 0.05), the number of CD cells decreased significantly (P <0.01), the ratio of CD4 / CD8 Was significantly higher (P <0.01). There was no significant change in the number of CD, CD, CD cells and CD4 / CD8 ratio in remission patients (P> 0.05). Chemiluminescence quantitative determination of neutrophil phagocytosis in patients with. Compared with the normal control group, the phagocytic function of neutrophils was significantly decreased in Graves’ disease (P <0.01). These indicators of the etiology and pathogenesis of Graves’s disease and post-treatment prognosis of a certain amount of help.