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基于充分认识到富含纤维素的食物在糖尿病治疗中的有益作用,目前已在研究采用能影响葡萄糖吸收和碳水化合物消化的物质作为糖尿病的辅助治疗药。业经开发的α-糖甙酶抑制剂miglitol和emiglitate在较低剂量时通过在小肠刷状缘的竞争性酶抑制作用,从而抑制淀粉和蔗糖的消化吸收。
Based on the full recognition of the beneficial effects of dietary fiber-rich foods in the treatment of diabetes, substances that affect glucose uptake and carbohydrate digestion have been studied as adjunct to diabetes mellitus. The developed α-glycosidase inhibitors miglitol and emiglitate inhibit the digestion and absorption of starch and sucrose through competitive enzyme inhibition at the brush border of the small intestine at lower doses.