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1961～1963年和1975～1977年为山东省两次克山病高发流行期,发病率为13.09/10万和6.73/10万。当时病区年人均收入38元和92元,人均口粮143kg 和217kg ,地瓜干占46～52%,以地瓜干为主食。1986～1991年为低发期或基本控制期,年发病率在0.037～0.042/10万,年人均收入为369元和548元,年人均口粮为281kg 和324kg ,小麦、玉米占27～35%,以细粮为主食,地瓜干很少食用。应用微机进行多元逐步回归分析显示:发病率与经济收入、人均口粮、小麦、玉米、大豆等呈负相关,与地瓜干呈正相关。
From 1961 to 1963 and from 1975 to 1977, two Keshan disease epidemic periods occurred in Shandong Province. The incidence rate was 13.09 / lakh and 6.73 / lakh respectively. At that time, the average annual income of the ward was 38 yuan and 92 yuan, per capita rations 143kg and 217kg, dry sweet potato accounted for 46 ~ 52% dry sweet potato as the staple food. From 1986 to 1991, it was a period of low incidence or basic control with annual incidence of 0.037 ~ 0.042 / 100000, annual per capita income of 369 yuan and 548 yuan, annual per capita rations of 281kg and 324kg, wheat and corn accounting for 27-35% , The main food staple food, dried sweet potatoes rarely eat. Multiple stepwise regression analysis using computer showed that the morbidity was negatively correlated with economic income, per capita ration, wheat, corn, soybean and so on, and positively correlated with dried sweet potato.