目的　探讨淤胆型婴儿巨细胞病毒 (CMV)肝炎患儿核素肝胆显像的变化及临床意义。方法　应用StarcamXR/T4 0 0型SPECT仪对 4 6例淤胆型婴儿CMV肝炎患儿行肝胆动静态显像 ,观察肝摄取和排泄功能与血清总胆红素值、肝酶 (ALT、γ GT)活性、肝脏病理征 (肝肿大、质地改变 )之关系。结果　 4 6例淤胆型婴儿CMV肝炎均有不同程度肝摄取和排泄异常 ,其中 2 8例肠道放射性时相延迟 ,18例肠道无放射性。此 18例患儿经治疗后再次核素肝脏显像检查肠道显影。结论　肝摄取和排泄功能与肝细胞损害和胆汁淤积程度密切相关 ;核素肝脏显像能评价肝胆损害程度 ,对肝外胆道闭锁鉴别具有实用价值。 Objective To investigate the changes and clinical significance of radionuclide hepatobiliary imaging in children with cholestatic baby cytomegalovirus (CMV). Methods Starcam XR / T4 0 0 SPECT was used to evaluate the hepatic bile duct dynamic imaging in 46 children with cholestatic infant CMV hepatitis. The effects of hepatic uptake and excretion on serum total bilirubin, liver enzymes (ALT, γ GT ) Activity, liver pathology (hepatomegaly, texture changes). Results All of the 46 cases of cholestatic infant CMV hepatitis had abnormal hepatic uptake and excretion, of which 28 cases had delayed gut radioactivity and 18 cases had no intestinal radioactivity. The 18 children after treatment of radionuclide liver imaging examination of intestinal development. Conclusions The uptake and excretion of liver are closely related to the degree of hepatocellular damage and cholestasis. The radionuclide liver imaging can evaluate the degree of hepatobiliary damage, which is of practical value in the identification of extrahepatic biliary atresia.