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目的探讨女性人乳头瘤状病毒(HPV)感染阳性率及临床意义。方法以2008-01-2009-12抚宁县妇幼保健院HPV检测的患者,对HPV阳性者行活检及病理学检查。结果该组人群1 452例,HPV阳性者429例,阳性率29.55%。阴道镜活检373例,病理为炎症者265例(71.05%),正常者20例(5.36%),CIN 88例(23.59%),其中CINⅠ68例(18.23%);CINⅡ13例(3.49%);CINⅢ7例(1.88%)。其年龄20～50岁,高危型HPV感染在各年龄组之间差异有统计学意义。结论高危型HPV感染是CIN发生的主要病因,结合组织活检,提高CIN的检出率。
Objective To investigate the positive rate and clinical significance of female human papillomavirus (HPV) infection. [Methods] The HPV positive patients in Funing County Maternal and Child Health Hospital from January 2008 to December 2009 were biopsied and pathologically examined. Results There were 1 452 cases and 429 HPV positive cases in this group, the positive rate was 29.55%. Colposcopic biopsy was performed in 373 cases, with pathological inflammation of 265 cases (71.05%), 20 cases (5.36%) with normal CIN, and 88 cases (23.59%) with CIN, of which CINⅠ was found in 18 cases (18.23%); Example (1.88%). The age of 20 to 50 years old, high-risk HPV infection in all age groups were statistically significant. Conclusion High-risk HPV infection is the main cause of CIN. Combined with biopsy, the detection rate of CIN is increased.