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肥大细胞对乳腺癌等肿瘤有抑制作用已有报导,为了探讨该细胞对胃癌的作用,用Gromari醛品红染色法检测并计数了46例胃癌癌组织、切缘正常组织及引流淋巴结中的肥大细胞。结果表明癌组织和切缘正常组织中细胞数大致相似,引流淋巴结中细胞数显著高于上述两种组织。有肿瘤转移的淋巴结和无转移的淋巴结中细胞数无显著差别。存活>3年患者中淋巴结肥大细胞数显著高于存活<3年者(P=0.03)。结果提示肥大细胞参与了机体对肿力的抑制作用。
Mast cells have inhibitory effects on breast cancer, etc. It has been reported that, in order to investigate the role of this cell in gastric cancer, the hypertrophy in 46 cases of gastric cancer tissues, marginal normal tissues, and draining lymph nodes was detected and counted by Gromari aldehyde fuchsin staining. cell. The results showed that the number of cells in the normal tissue of the cancerous tissue and the margin was similar, and the number of cells in the draining lymph nodes was significantly higher than that in the above two tissues. There was no significant difference in the number of cells in lymph nodes with and without metastasis. The number of lymph node mast cells in patients who survived >3 years was significantly higher than those who survived <3 years (P=0.03). The results suggest that mast cells participate in the body’s inhibition of swelling.