急性胰腺炎(AP)病情凶险,并发症多且病死率高,至今其发病机制尚未完全阐明。近年来,随着分子生物技术的发展,不少学者从基因分子水平研究AP的发病机制及病理过程,发现AP的发生及发展存在个体差异,从细胞因子基因多态性进一步阐明了AP的发病机制,并通过明确AP患者的细胞因子多态性特点,采取个体化的防治措施。 Acute pancreatitis (AP) is extremely dangerous and has many complications and high mortality rate. Up to now, its pathogenesis has not been fully elucidated. In recent years, with the development of molecular biology technology, many scholars have studied the pathogenesis and pathological process of AP from the molecular level of gene, and found that there are individual differences in the occurrence and development of AP. The pathogenesis of AP is further elucidated from the gene polymorphisms of cytokines Mechanism, and through the clear characteristics of AP patients with cytokine polymorphisms, to take individual control measures.