丙帕他莫(propacetamol hydrochloride,1,二乙胺基乙酸4-乙酰胺基苯酯盐酸盐)作为扑热息痛的前体药物近年来在国外受到重视。扑热息痛注射剂的使用,避免了肝脏的首过效应,减小了用药剂量。但其对溶剂系统、温度、pH等条件要求较高,稳定性较差。而丙帕他莫易溶于水,稳定性好,注射给药后可迅速而完全地转变为扑热息痛。本品在法国制成1g装注射剂用于治疗各种病因的疼痛与发热症状。 Propacetamol hydrochloride (1, diethylaminoacetic acid 4-acetamidophenyl ester hydrochloride) as a prodrug of paracetamol in foreign countries in recent years attention. The use of paracetamol injection, to avoid the first pass of the liver effect, reducing the dosage. But its solvent system, temperature, pH and other conditions require higher stability is poor. Propranolol is readily soluble in water and has good stability. It can be rapidly and completely converted to paracetamol after injection. This product made in France 1g injection for the treatment of various causes of pain and fever symptoms.