论文部分内容阅读
重组人腺病毒5型(HAd5)载体是一种良好的粘膜或皮下免疫疫苗抗原传递体系。本文作者用表达牛疱疹病毒Ⅰ型(BHV-1)完整或截短糖蛋白D(gD或tgD)的HAd5载体免疫小鼠,观察诱发特异的抗体和T细胞应答情况。
Recombinant human adenovirus type 5 (HAd5) vector is a good mucosal or subcutaneous immune vaccine antigen delivery system. The authors immunized mice with a HAd5 vector expressing either complete or truncated glycoprotein D (gD or tgD) of bovine herpesvirus type 1 (BHV-1) and observed the induction of specific antibody and T cell responses.