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[目的]分析杭州某高校教师心血管病危险因素随体质指数(body mass index,BMI)增加的变化情况,为杭州高校教工预防心血管疾病提供理论依据。[方法]将436名教师分为体重未超标组(264人)、超重组(135人)、肥胖组(37人);比较各组血压、血糖、血脂、同型半胱氨酸(homocysteine,Hcy)、脂蛋白(a)[liporotein(a),LP(a)]、胱抑素C(cystatin,Cys-C)、超敏C反应蛋白(high sensitivity C reactive protein,hs CRP)的差异;并统计各体重组教工BMI和Hcy、LP(a)、Cys-C、hs CRP的相关性。[结果]与体重未超标组比较,超重组和肥胖组教工的血压、血糖、血脂、Hcy、LP(a)、hs CRP均升高(P<0.05);与超重组比较,肥胖组教工的血压、血糖、LP(a)升高(P<0.05);超重组和肥胖组教师的BMI和Hcy、LP(a)、hs CRP具有正相关关系(P<0.05)。[结论]超重及肥胖与其他心血管危险因素存在聚集现象,对于高校教师中超重、肥胖者,应注意检查和发现多重心血管病危险因素的并存。
[Objective] To analyze the changes of risk factors of cardiovascular diseases in a university teacher in Hangzhou with the increase of body mass index (BMI), and provide the theoretical basis for the prevention and treatment of cardiovascular diseases in Hangzhou colleges and universities. [Methods] A total of 436 teachers were divided into two groups: normal control group (264), overweight group (135) and obesity group (37). Blood pressure, blood glucose, blood lipid, homocysteine ), Lipoprotein (a), LP (a)], cystatin C (Cys-C) and high sensitivity C reactive protein (hs CRP) The correlation between BMI and Hcy, LP (a), Cys-C and hs CRP was analyzed. [Results] The blood pressure, blood glucose, blood lipid, Hcy, LP (a) and hs CRP of overworked and obese group were significantly higher than those of the overweight and obesity group (P <0.05). Compared with the overweight group, Blood pressure, blood glucose and LP (a) increased (P <0.05). There was a positive correlation between BMI and Hcy, LP (a) and hs CRP in overweight and obesity group (P <0.05). [Conclusion] Overweight, obesity and other cardiovascular risk factors are aggregated. For those overweight and obese among college teachers, we should pay attention to the coexistence of risk factors of multiple cardiovascular diseases.