十二指肠溃疡患者同时伴发胃癌罕见,我院从1967年～1979年共收治3例,现结合文献复习报告分析如下:病例报告例1.男,42岁。上腹疼痛伴频繁呕吐20天.有反复发作的胃病史15年。二年前曾因十二指肠球部前壁溃疡穿孔行修补术,嗣后服甲氰咪胍症状缓解,停药后复发,近半年来腹痛失去规律性.住院后在硬膜外麻醉下施行毕氏Ⅱ式胃大部切除术。病理检查:在切除标本胃小弯侧距幽门残端3厘米处见一直径2厘米溃疡,呈碟形,溃疡底呈灰白色, Duodenal ulcer patients accompanied by rare gastric cancer, our hospital from 1967 to 1979 were treated in 3 cases, now combined with the literature review report analysis is as follows: case report case 1. Male, 42 years old. Epigastric pain with frequent vomiting for 20 days. A history of recurrent stomach problems for 15 years. Two years ago, he had been repaired by perforation of the anterior wall of the duodenal bulb and he was relieved after taking cimetidine. After the drug relapsed, his abdominal pain lost regularity in the past six months. After the hospitalization, it was performed under epidural anesthesia. Pei’s type II gastrectomy. Pathological examination: A 2 cm diameter ulcer was seen 3 cm away from the pyloric stump at the side of the resection specimen. The ulcer was pale and white.