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四氯化碳(carbon tetrachloride,CCl4)是一种强烈的能够引起肝细胞坏死的化合物,其可在动物体内部分重现人类肝病模式,故一直被研究者作为诱发各种肝损伤模型的造模剂,以期阐明肝脏毒性的发生机制。目前,开发新药和保健食品的规范中仍使用CCl4来建立动物模型,随着各种新的研究
Carbon tetrachloride (CCl4) is a potent compound that induces necrosis of liver cells that partially reproduces human liver disease patterns in animals and has long been used by researchers as a model for inducing various liver injury models Agent, in order to clarify the mechanism of liver toxicity. At present, CCl4 is still used to establish animal models in the norms of developing new drugs and health food products. With various new research