淋巴瘤是一种常见的血液系统恶性肿瘤,CHOP方案作为一线化疗方案,其临床有效率达80%,但仍有50%患者难以达到完全缓解,影响患者生存,且用该方案化疗,仍有50%~60%复发,对于复发或难治性淋巴瘤,目前缺乏标准治疗方案,我院采用ESHAP方案治疗复发或难治性淋巴瘤18例,取得一定疗效,现 Lymphoma is a common hematological malignancy. The CHOP regimen, as a first-line chemotherapy regimen, achieves a clinically effective 80% rate, but it is still difficult to achieve complete remission in 50% of patients and affects patient survival. Chemotherapy with this regimen remains 50% ~ 60% relapse, for relapsed or refractory lymphoma, the current lack of standard treatment regimen, ESHAP regimen in our hospital for the treatment of relapsed or refractory lymphoma in 18 cases, and achieved a certain effect, and now