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肿瘤转移抑制基因KAIL在胰腺癌中的突变方式已于近日被沈阳军区总医院消化内科主任郭晓钟博士等发现。研究者据此认为,胰腺癌转移可由基因突变所导致,这一发现为人们从分子水平认识胰腺癌的发生、发展及浸润转移提供了最新理论,也为控制和预测此癌的复发转移提供了临床实际应用的依据。 癌变细胞转移是胰腺癌的突出特征之一。据统计,仅在发病初期就有80％的患者出现转移,40％的患者在术后仍有淋巴结及远端器官转移,对此,医学界至今尚无效果显著的治疗对策,胰腺癌的死亡率在所有癌症中位列第五,并呈上升趋势。1995年,郭晓
The mutation of the tumor metastasis suppressor gene KAIL in pancreatic cancer has recently been discovered by Dr. Guo Xiaozhong, Director of Gastroenterology, General Hospital of Shenyang Military Region. Researchers believe that the metastasis of pancreatic cancer can be caused by genetic mutations. This discovery provides the latest theory for understanding the occurrence, development and invasion and metastasis of pancreatic cancer at the molecular level. It also provides a control and prediction of the recurrence and metastasis of this cancer. The basis of clinical practical application. Cancerous cell metastasis is one of the prominent features of pancreatic cancer. According to statistics, 80% of patients have metastases only in the early stage of disease. 40% of patients still have lymph node and distant organ metastases after surgery. For this reason, the medical community has so far no effective treatment measures, and the death of pancreatic cancer. The rate ranks fifth in all cancers and is on the rise. In 1995, Guo Xiao