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目的:探讨胃间质瘤(GST)的诊断和治疗措施。方法:回顾性分析我院2000年4月至2006年3月近6年收治的11例胃间质瘤患者的临床表现、辅助检查、手术治疗方式及病理结果。结果:临床以消化道出血、腹部肿块表现为主,症状无特异性,所有病例术前均行胃镜及CT检查,均行手术治疗,其中6例行肿瘤楔形切除,5例行胃大部切除术,病理诊断良性5例(45.5%)交界性1例(9%),恶性5例(45.5%)。随访时间3个月至5年,死亡1例,死于腹腔广泛转移。结论:胃间质瘤缺乏特异的临床表现,术前诊断困难,胃镜和CT可发现病变,诊断以病理诊断为准,其中免疫组化结果为重要诊断依据,治疗以手术切除为主。
Objective: To investigate the diagnosis and treatment of gastric stromal tumor (GST). Methods: A retrospective analysis of 11 cases of gastric stromal tumors in our hospital from April 2000 to March 2006 nearly 6 years clinical manifestations, laboratory examinations, surgical treatment and pathological findings. Results: The clinical manifestations of gastrointestinal bleeding and abdominal mass were non-specific. All patients underwent endoscopy and gastroscopy preoperatively. All patients underwent surgical treatment. Among them, 6 patients underwent wedge resection and 5 underwent subtotal gastrectomy Five cases (45.5%) were diagnosed as benign and 5 cases (45.5%) were clinically diagnosed as borderline (9%) and malignant. Follow-up time of 3 months to 5 years, 1 died, died of extensive metastasis in the abdominal cavity. Conclusions: Gastric stromal tumors lack of specific clinical manifestations, preoperative diagnosis is difficult, gastroscopy and CT lesions can be found, the diagnosis is based on pathological diagnosis, including immunohistochemical findings as an important basis for diagnosis, the main surgical treatment.