论文部分内容阅读
对50例晚期食管贲门癌包括伴有锁骨上淋巴结已有转移的病人,以手术切除为主,术后辅以化疗、放疗行综合性治疗。每例病人用卡铂200mg+5％葡萄糖液500ml静滴,每日1次,3天为一疗程,每月1次×3疗程。有癌残留或附近脏器有癌受侵润,切除不彻底者给予常规放疗,放疗剂量为40～70Gy。手术并发症7例:胸内吻合口瘘1例,颈部吻合口小瘘1例,呼吸衰竭2例,死亡率为4％,原因:1例为吻合口瘘感染导致主动脉破裂大出血,另1例呼吸衰竭死亡。近期随访结果:本组48例,死亡18例,死亡原因绝大多数是远处转移或复发。术后半年内死亡4例,1年内死亡7例,2年内死亡7例,总死亡率40％,2年内近期存活率63.3％。
For 50 cases of advanced esophageal and cardia cancers, including those with metastases of supraclavicular lymph nodes, surgical resection was the main method, followed by chemotherapy and radiotherapy for comprehensive treatment. Each patient was intravenously infused with carboplatin 200 mg + 5% glucose 500 ml once daily for 3 days as a course of treatment and once a month for 3 courses of treatment. Cancerous residual or nearby organs were invaded by cancer. Incomplete removal was given to conventional radiotherapy. The radiation dose was 40 to 70 Gy. Surgical complications in 7 cases: intrathoracic anastomotic fistula in 1 case, neck anastomosis in 1 case, respiratory failure in 2 cases, mortality rate was 4%, reason: 1 case of anastomotic leakage caused by aortic rupture bleeding, another One patient died of respiratory failure. Recent follow-up results: 48 cases in this group, 18 deaths, the vast majority of deaths are distant metastasis or recurrence. Four patients died within six months after operation. Seven patients died within one year, seven patients died within two years, and the total mortality rate was 40%. The recent survival rate was 63.3% within two years.