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目的探讨输精管结扎对中老年前列腺症状和患前列腺癌风险的影响。方法调查北京、湖北、江苏309名已行输精管结扎的中老年人,同时按1∶2比例选取618名年龄匹配的未结扎中老年人作为对照,以填写调查问卷方式计算国际前列腺症状评分表(international prostate symptom score,IPSS)评分,留取外周血进行前列腺特异性抗原(prostate specific antigen,PSA)和游离PSA检测,比较两组间差异。结果在所调查的人群中,经矫正教育程度等因素后,输精管结扎组和非结扎组之间IPSS评分、PSA水平、游离PSA和游离PSA百分比比较差异无统计学意义(P>0.05)。结论输精管结扎术不影响前列腺的症状,也不提高前列腺癌的风险。
Objective To investigate the effects of vasectomy on the risk of prostate cancer in middle-aged and elderly people. Methods A total of 618 middle-aged and elderly patients with vasectomies were investigated in Beijing, Hubei and Jiangsu Provinces. At the same time, 618 age-matched middle-aged and elderly patients without age-related disease were selected according to the ratio of 1: 2. The questionnaire was used to calculate the International Prostate Symptom Score Table international prostate symptom score (IPSS) score, peripheral blood was collected for the detection of prostate specific antigen (PSA) and free PSA, and the differences between the two groups were compared. Results There was no significant difference in IPSS score, PSA level, percentage of free PSA and free PSA between the vasectomized and non-ligated groups in the surveyed population, after corrective education and other factors (P> 0.05). Conclusion Vasectomy does not affect the symptoms of prostate and does not increase the risk of prostate cancer.