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目的:总结1991年5月~2000年12月间71例食管癌患者行内翻拔脱术及其综合治疗的结果。方法:71例食管癌患者,中位年龄62岁。其中Ⅰ期40例,Ⅱa期26例,Ⅱb期4例,Ⅳ期1例,均采用食管内翻拔脱术治疗,接受术前辅助放疗4000cGy者9例,术后辅助放疗6000cGy者17例,术前新辅助化疗者5例。结果:术后1、3、5年的生存率为:Ⅰ期100.00%、91.43%、86.21%;Ⅱa期92.00%、83.33%、57.14%;Ⅱb期75.00%、50.00%、50.00%;Ⅳ期100.00%、0、0;全组71例患者1、3、5年总生存率分别为95.71%、86.89%、71.70%。并发症发生率为12.68%。结论:食管内翻拔脱术结合放、化疗将使不能耐受经胸或不需经胸手术的Ⅱa期及更早期的食管癌患者获益。
OBJECTIVE: To summarize the results of 71 cases of esophageal cancer patients who underwent internal lift-off surgery and its comprehensive treatment from May 1991 to December 2000. Methods: 71 patients with esophageal cancer, the median age of 62 years. Among them, 40 cases were stage Ⅰ, 26 cases were stage Ⅱa, 4 cases were stage Ⅱb and 1 stage was stage Ⅳ. All cases were treated by esophageal varus extraction, 9 cases received preoperative adjuvant radiotherapy of 4000cGy, 17 cases of postoperative adjuvant radiotherapy of 6,000cGy, Preoperative neoadjuvant chemotherapy in 5 cases. Results: The survival rates at 1, 3 and 5 years after operation were 100.00%, 91.43% and 86.21% in stage Ⅰ, 92.00%, 83.33% and 57.14% in stage Ⅱa, 75.00%, 50.00% and 50.00% in stages Ⅱb, 100.00%, 0,0; The overall survival rates at 1, 3 and 5 years in the 71 patients were 95.71%, 86.89% and 71.70% respectively. The complication rate was 12.68%. Conclusion: The combination of esophageal varus extraction and chemotherapy will benefit patients with stage Ⅱa and earlier esophageal cancer who can not tolerate or not undergo transthoracic surgery.