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目的 探讨一种治疗小儿非溃疡性消化不良 (NUD)的新方法。方法 治疗组 60例用阿莫西林、丽珠得乐、西米替丁 (甲氰咪胍 )及多潘立酮 (吗丁啉 )四联治疗 ,1个月为一疗程 (其中阿莫西林只连用 2周 )。应用剂量 :阿莫西林5 0～ 10 0mg/ (kg·d)分 3次口服 ;丽珠得乐 5～ 8mg/ (kg·d)分 3次口服 ;西米替丁 5～ 10mg/ (kg·d)晚上顿服或分早晚 2次口服 ;多潘立酮 0 3mg/ (kg·d)分 3次口服。对照组 15例 ,单用多潘立酮 1个月 ,剂量同前。结果 治疗组 1个疗程后全部患儿 ( 10 0 % )症状消失 ;对照组 1个疗程后 10例 ( 67% )症状消失 ,( χ2 =2 1 4,P <0 0 1)。结论 应用阿莫西林、丽珠得乐、西米替丁、多潘立酮四种药物联合治疗小儿NUD比单用多潘立酮疗效好。
Objective To explore a new method for treating non-ulcer dyspepsia (NUD) in children. Methods The treatment group of 60 patients treated with amoxicillin, Livzonde, cimetidine (cimetidine) and domperidone (domperidone) quadruple therapy, one month for a course of treatment (including amoxicillin only 2 week). Application dose: Amoxicillin 50 ~ 10 0mg / (kg · d) orally 3 times; Livzonadol 5 ~ 8mg / (kg · d) orally 3 times; cimetidine 5 ~ 10mg / (kg · D) orally at night or morning and evening orally 2 times; domperidone 0 3mg / (kg · d) orally 3 times. The control group of 15 cases, single domperidone 1 month, the same dose. Results All the patients (100%) disappeared after one course of treatment in the treatment group, and disappeared in 10 cases (67%) after one course of treatment in the control group (χ2 = 2 1 4, P 0 01). Conclusion The combination of Amoxicillin, Livzonde, Cimetidine and Domperidone in the treatment of children with NUD is more effective than domperidone alone.