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目的了解喀什试点内脏利什曼病的人群感染状况。方法选择喀什市内脏利什曼病发病率较高的村为试点,在入户普查的同时开展人群血清学调查和利什曼素皮内试验,运用SAS软件对调查结果进行综合分析。结果不同年龄组之间皮试阳性率差异有统计学意义(χ2=11.53,P<0.05),皮试阳性率随年龄的增加有逐渐增高的趋势。当地内脏利什曼病患者与既往隐性感染者之比为1∶9。试点地区曾感染过内脏利什曼病的免疫人群占36.15%(60/166),从未感染过内脏利什曼病的易感人群占61.45%(102/166),无临床症状的现感染人群占2.41%(4/166)。结论试点地区内脏利什曼病的流行状况仍然比较严重,无症状现感染者所占比例较高,具有潜在传染源的流行病学意义。
Objective To understand the prevalence of visceral leishmaniasis in Kashgar. Methods The village with high incidence of visceral leishmaniasis in Kashgar was selected as the pilot. At the same time, the serological investigation and the Leishman skin intradermal test were conducted at the time of household census. The SAS software was used to analyze the survey results comprehensively. Results There was a significant difference in the positive rate of skin test between different age groups (χ2 = 11.53, P <0.05). The positive rate of skin test increased gradually with age. The ratio of local visceral leishmaniasis to the previously implicated ones is 1: 9. 36.15% (60/166) of the immunized people who had visceral leishmaniasis in the pilot area, 61.45% (102/166) of the susceptible people who had never had visceral leishmaniasis, and no clinical signs of infection The population accounted for 2.41% (4/166). Conclusions The prevalence of visceral leishmaniasis in the experimental area is still relatively serious, with a high prevalence of asymptomatic infections and an epidemiological significance of potential sources of infection.