慢性粒细胞性白血病是一种单克隆骨髓增生性疾病,起源于多能干细胞的肿瘤样转变。尽管发病时血小板数量增多,但仍常伴有出血。本组观察7例慢粒患者血小板,发现其超微结构明显异常:①细胞大小悬殊,多数为2μ以下的小细胞,但同时常见5至10μ的巨大血小板;②多数细胞胞浆致密性改变,而正常应具中等电子密度的 Chronic myelogenous leukemia is a monoclonal myeloproliferative disease that has originated in the tumor-like transition of pluripotent stem cells. Although the incidence of platelets increased, but often accompanied by bleeding. This group observed seven patients with chronic granulocyte platelet and found that the ultrastructural abnormalities: ① cell size disparity, the majority of small cells below 2μ, but at the same time common 5 to 10μ huge platelets; ② most of the cytoplasm density changes, Normal should have a medium electron density