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目的探讨临床中丙戊酸钠治疗癫痫临床疗效,并分析其安全性。方法将2011年1月至2014年2月间收治的72例癫痫患者随机分为研究组与对照组两组,对照组给予常规治疗,研究组在常规治疗基础上给予丙戊酸钠治疗,观察两组的临床治疗效果。结果研究组总有效率88.9%,高于对照组的77.8%,统计学有意义(P<0.05)。研究组不良发生率为8.4%,低于对照组的27.8%,统计学有意义(P<0.05)。结论癫痫患者在常规治疗基础上应用丙戊酸钠可以提高临床治疗有效率,且治疗过程中的不良反应少,安全性高,值得临床中应用与推广。
Objective To investigate clinical efficacy of sodium valproate in the treatment of epilepsy and analyze its safety. Methods Seventy-two patients with epilepsy who were admitted between January 2011 and February 2014 were randomly divided into study group and control group. The control group was given routine treatment. The study group was treated with sodium valproate on the basis of routine treatment. Two groups of clinical treatment. Results The total effective rate of the study group was 88.9%, which was higher than that of the control group (77.8%), with statistical significance (P <0.05). The incidence of adverse events in the study group was 8.4%, which was lower than that in the control group (27.8%), which was statistically significant (P <0.05). Conclusion Epilepsy patients in the conventional treatment based on the application of sodium valproate can improve the efficiency of clinical treatment, and the adverse reactions in the course of treatment less, high safety, it is worth the clinical application and promotion.