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目的研究甘利欣(甘草酸二铵)在慢性乙型肝炎治疗中的临床效果。方法选取30例慢性乙肝患者,随机分成治疗组和对照组两组。其中治疗组患者选择甘利欣进行治疗,同时还予以常规性保肝药物以及维生素进行治疗;对照组患者使用强力宁治疗。结果在治疗中,使用甘利欣进行治疗的治疗组患者,在用药期间没有1例患者因为出现副作用后停药。在随访过程中没有发现血钾降低以及血钠或是血压过高患者,也没有ALT的反跳现象。对照组中有2例患者由于病情加剧而停药,还有3例患者在减量过程中发生了ALT的反跳现象。结论在慢性肝炎治疗中,甘利欣能改善患者症状,加快肝功能的恢复,临床效果确切且安全。
Objective To study the clinical effect of Glycyrrhizin (diammonium glycyrrhizinate) in the treatment of chronic hepatitis B patients. Methods Thirty patients with chronic hepatitis B were selected and randomly divided into treatment group and control group. Among them, the patients in the treatment group were treated with Glycyrrhizin, meanwhile they were also treated with routine hepatoprotective drugs and vitamins. The patients in the control group were treated with prednisolone. Results In the treatment, patients in the treatment group treated with Glycyrrhizin did not discontinue treatment because of side effects. During the follow-up no hypokalemia was found and there was no rebound of ALT in patients with hyponatremia or hyperparathyroidism. In the control group, 2 patients discontinued due to exacerbations, and 3 patients experienced ALT rebound during weight loss. Conclusion In the treatment of chronic hepatitis, Glycyrrhizin can improve the symptoms of patients and speed up the recovery of liver function, the clinical effect is exact and safe.