在日本 ,随着开展降低胆固醇宣传活动和有效减低脂质药物的问世 ,致使心血管疾病减少 ,但相对的伴糖尿病的心血管疾病的死亡率却明显增加。这也是美国糖尿病患者的最主要死因 ,其中占半数以上为冠状动脉硬化性心脏病。据预测本世纪前叶 ,由于遗传性的胰岛素分泌贮备能力的缺乏 In Japan, with the promotion of cholesterol-lowering activities and the effective reduction of lipid-related drugs, cardiovascular diseases are reduced, but the mortality rate of the relative diabetes-related cardiovascular diseases is significantly increased. This is also the leading cause of death among diabetic patients in the United States, of which more than half are coronary heart disease. It is predicted that the first half of this century due to the lack of genetic insulin secretion reserve capacity