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目的：骼内动脉灌注化疗预防浸润性膀胱肿瘤术后复发。方法：浸润性膀胱肿瘤行膀胱部份切除或全切术后，骼内动脉远端插管与皮下埋置化疗泵，术后定期经皮穿刺注射丝裂霉素与卡铂等化疗药物，观察药物作用与肿瘤复发情况等以确定其临床疗效。结果：１４ 例浸润性膀胱肿瘤（Ｔ３ 期１１ 例，Ｔ４ 期３ 例） 除２例近期埋泵处皮肤红肿与１ 例臀部皮肤潮红及臀肌疼痛外，未见血象降低及骨髓抑制等不良反应，随访２ 例术后１１～３０ 个月未见肿瘤复发。结论：该方法将化疗药物直接作用于病变部位有效地杀灭残存与复发的肿瘤细胞，并可减少药物的毒副作用，方法简便，近期疗效满意。
OBJECTIVE: Internal iliac arterial infusion chemotherapy is used to prevent postoperative recurrence of invasive bladder tumors. METHODS: After partial bladder resection or total resection of invasive bladder tumors, the internal iliac artery was cannulated and subcutaneously placed with a chemotherapy pump, and mitomycin C and carboplatin and other chemotherapy drugs were injected at regular intervals after operation. The role of drugs and tumor recurrence, etc. to determine its clinical efficacy. Results: 14 cases of invasive bladder tumors (11 cases at T3 stage and 3 cases at T4 stage). In addition to 2 cases of skin reddening at the buried pump and 1 case of hip flushing and gluteal muscle pain, no adverse effects such as decreased blood count and bone marrow suppression were observed. No tumor recurrence was found in 11 patients up to 11 months after follow-up. Conclusion: The method can directly effect the chemotherapy drugs on the lesions to effectively kill the residual and recurrent tumor cells, and reduce the toxic and side effects of the drugs. The method is simple and the short-term effect is satisfactory.