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目的:探讨远缘链球菌与乳牙龋病的关系。方法:采有TYCSB培养基作细菌筛选,运用分子遗传学手段即DNA的G+ C mol% 测定作最终鉴定。结果:患龋儿童组与无龋儿童组变形链球菌检出率有显著差异(P<0 .01),远缘链球菌检出率有显著差异(P< 0.05) ;患龋儿童组中能同时检出变形链球菌和远缘链球菌的群体,其龋失补牙数、龋失补牙面数及平滑面龋数均与只能检出变形链球菌的群体有显著差异( P< 0.01) 。结论:变形链球菌是龋病的主要致病菌,远缘链球菌对龋病过程有协同作用,与乳牙平滑面龋的发生、发展有关。
Objective: To investigate the relationship between Streptococcus sobrinus and deciduous dental caries. Methods: TYCSB culture medium was selected for bacterial screening, using molecular genetic means DNA G + C mol% determination for the final identification. Results: The prevalence of Streptococcus mutans was significantly different between caries-bearing children and caries-free children (P <0.01), and the detection rate of Streptococcus sobrinus was significantly different (P <0.05). In caries-bearing children In the group of S. mutans and Streptococcus sobrinus detected at the same time, the number of dental caries lost, dental caries lost, and smooth caries were significantly different from those with only S. mutans detected (P <0 .01). Conclusion: Streptococcus mutans is the main pathogen of dental caries. Streptococcus sobrinus has a synergistic effect on carious process, which is related to the occurrence and development of deciduous caries of deciduous teeth.