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目的观察泡沫硬化剂注射治疗皮肤血管瘤及血管畸形的疗效。方法 2011年11月至2014年11月期间,对笔者所在医院科室收治的53例不同类型的皮肤血管瘤及血管畸形患者采用泡沫硬化剂瘤内注射治疗,根据患者年龄、瘤体大小和深度决定用药剂量和注射次数,注射最大剂量不超过6 m L/次,2次注射的间隔时间为2~4周。结果 53例患者中男20例,女33例;年龄1个月~40岁,中位年龄1.6岁;瘤体大小为1.0 cm×(1.0~2.0)cm×5.0 cm。53例患者均完成全程治疗,注射治疗1~6次,平均注射治疗3次,并经6个月随访,其中达到Ⅰ级疗效者2例(3.8%),Ⅱ级疗效者5例(9.4%),Ⅲ级疗效者10例(18.9%),Ⅳ级疗效者36例(67.9%);1例出现局部皮肤破溃,经换药处理后创面愈合。结论泡沫硬化剂注射治疗皮肤血管瘤及血管畸形安全有效。
Objective To observe the efficacy of foam sclerotherapy for the treatment of cutaneous hemangiomas and vascular malformations. Methods From November 2011 to November 2014, 53 cases of different types of cutaneous hemangiomas and vascular malformations admitted to the hospital department of our hospital were treated with intratumoral injection of foam sclerotherapy, which was decided according to patient’s age, tumor size and depth The dosage and the number of injections, the maximum dose of injection does not exceed 6 m L / time, 2 injection interval of 2 to 4 weeks. Results There were 20 males and 33 females in 53 cases. The age ranged from 1 month to 40 years and the median age was 1.6 years. The tumor size was 1.0 cm × (1.0 ~ 2.0) cm × 5.0 cm. Fifty-three patients completed the whole course of treatment. The patients were treated with injection for 1 to 6 times with an average of 3 injections. After 6 months of follow-up, 2 patients (3.8%) achieved grade I and 5 (9.4% ), Grade Ⅲ curative effect in 10 cases (18.9%), grade Ⅳ curative effect in 36 cases (67.9%); 1 case of local skin ulceration, wound healing after dressing change. Conclusions Foam sclerotherapy is safe and effective in the treatment of cutaneous hemangiomas and vascular malformations.