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我科从1988年起用巯甲丙脯酸(巯甲)治疗了17例糖尿病肾病,现将结果报告如下。 对象与方法 糖尿病肾病患者17例,男12例,女5例,年龄38～66岁,其中15例合并糖尿病视网膜病变,11例属增殖型病变。12例伴有高血压,血压≥21.3/12.0 kPa,5例血压正常。糖尿病肾病的诊断标准为:尿白蛋白>15μg/分,测3次,中段尿培养阴性(3次),临床上未查到引起蛋白尿的其它原因。17例中3例作肾穿刺活检证实为糖尿病肾病。巯甲治疗前测血糖,HbA_1c,血K、Na_1,BUN,Ccr,
17 cases of diabetic nephropathy were treated with captopril in our department from 1988, and the results are reported as follows. Subjects and Methods Diabetic nephropathy in 17 patients, 12 males and 5 females, aged 38 to 66 years, of which 15 cases of diabetic retinopathy, 11 cases of proliferative lesions. 12 cases with hypertension, blood pressure ≥ 21.3 / 12.0 kPa, 5 cases of normal blood pressure. Diabetic nephropathy diagnostic criteria: urinary albumin> 15μg / min, measured 3 times, the middle urine culture negative (3 times), clinically not found other causes of proteinuria. Three of 17 cases were confirmed as diabetic nephropathy by renal biopsy. Captopril before treatment of blood glucose, HbA_1c, blood K, Na_1, BUN, Ccr,