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茜草科耳草属植物Qldenlandia affims的水煎剂在非洲民间用作口服催产药,在分娩前服用100克植物的茎、叶水煎物能引起强烈子宫收缩,并缩短分娩时间。这种水提物对离体小鼠子宫或妊娠子宫肌条,人体子宫都有显著的催产活性。一克植物的提取物对小鼠离体子宫相当0.2单位的催产素。作者在二篇文章中研究了此植物中的催产成份,其中一个有效成份,经化学鉴定、生物活性测定,并与已知品对照,证实是5-羟色胺,每克干植物得纯品25微克。
The water decoction of Qiladenia affims of the genus Rubia is used as an oral oxytocin in the African country. Before taking delivery, it takes 100 grams of the plant’s stems and leaf water extracts can cause intense uterine contractions and shorten the delivery time. This water extract on isolated mouse uterus or pregnant uterine muscle strips, the human uterus have significant oxytocin activity. An extract of one gram of plant corresponds to 0.2 unit of oxytocin in mouse uterus in vitro. In two articles, the authors studied the oxytocin component of this plant. One of the active ingredients, chemically identified, tested for biological activity, was compared to a known product and found to be serotonin, yielding 25 micrograms of pure product per gram of dry plant .