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本文采用ＳＯＤ／ＬＰＯ比值这一指标观测了不同年龄组健康成人ＳＯＤ／ＬＰＯ比值的变化及冠心病、糖尿病及肿瘤患者对这一指标的影响。结果表明：正常人ＬＰＯ水平随年龄逐渐增高，而ＳＯＤ活性逐渐下降，ＳＯＤ／ＬＰＯ比值显著下降。冠心病、糖尿病患者比正常组ＬＰＯ水平更高，ＳＯＤ活性更低，尤其ＳＯＤ／ＬＰＯ比值下降显著，而肿瘤患者的ＬＦＯ、ＳＯＤ变化更为显著。这提示自由基增加是冠心病、糖尿病及肿瘤患者的发病机理之一。
In this paper, SOD / LPO ratio of this indicator observed in different age groups healthy adults SOD / LPO ratio changes and coronary heart disease, diabetes and cancer patients on this index. The results showed that the level of LPO in normal subjects increased gradually with the increase of age, while the activity of SOD decreased gradually and the ratio of SOD / LPO decreased significantly. In patients with coronary heart disease and diabetes, LPO level was higher and SOD activity was lower than normal group, especially the ratio of SOD / LPO was significantly decreased, while LFO and SOD in cancer patients were more obvious. This suggests that increased free radicals is one of the pathogenesis of coronary heart disease, diabetes and cancer patients.