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作者回顾分析了110例颅内生殖细胞瘤患者,旨在确定颅内生殖细胞瘤在放疗前经病理证实者所占的百分比以及放射野的选择对治疗结果的影响。66例(62%)是根据患者在接受10~20Gy所谓“诊断性放疗”后CT或MRI影像上肿瘤退缩情况而诊断为颅内生殖细胞瘤的。只有41例(38%)在放疗前经病理证实为生殖细胞瘤,这个百分比随治疗时间而有所增加,1978~1983年为26%,1984~1989
The authors retrospectively analyzed 110 patients with intracranial germinomas that sought to determine the percentage of intracranial germinomas that had been pathologically confirmed prior to radiotherapy and the effect of radiation field selection on outcome. Sixty-six patients (62%) were diagnosed as intracranial germinomas on the basis of tumor regression on CT or MRI images after 10 to 20 Gy of so-called “diagnostic radiotherapy”. Only 41 (38%) were pathologically confirmed as germinomas prior to radiotherapy, with the percentage increasing with treatment time from 26% in 1978-1983 to 1984-1989