应激性溃疡为一多发、急性、浅表性胃粘膜糜烂。病人都为严重损伤或重症病人。出血机会随病的严重度和存在的危险因素数目而增加。应激性溃疡发病快,常在严重损伤或多器官外伤后几小时内发生,尤其在合并革兰氏阴性菌菌血症休克的病人。在肾移植、脑损伤及其他损伤病人的内窥镜检查证实,应激性溃疡的发病率高达100%。这种病人的出血死亡率可高达80%。在预防上主要集中围绕于应用甲氰咪呱和抗酸剂。仅管抗酸剂的效果似乎比甲 Stress ulcer is a multiple, acute, superficial gastric mucosal erosion. Patients are seriously injured or critically ill patients. The chance of bleeding increases with the severity of the disease and the number of risk factors present. Stress ulcers develop rapidly and often occur within a few hours after severe injury or multiple organ trauma, especially in patients with Gram-negative bacteremia. Endoscopy in patients with kidney transplants, brain injuries and other injuries confirms that the incidence of stress ulcers is as high as 100%. The bleeding death rate of such patients can be as high as 80%. The main focus of prevention is on the use of cimetidine and antacids. The effect of antacids seems to be better than a