近年来药物诱发支气管哮喘日被临床工作者所重视。目前已知比较常见的药物有:β-受体阻滞剂,解热镇痛药,雾化吸入剂(异丙肾上腺素,多粘菌素B,脑垂体提取物吸入剂,乙酰半胱氨酸,色甘酸二钠)及其它一些药物(匹罗卡因,甲酰胆硷和新斯的明)。但复方新诺明诱发哮喘并不多见,现报告1例如下。病历介绍患者女孩,4岁。近一年来反复发生上呼吸道感染,每次都服用复方新诺明治疗。于1985年5月17日患上呼吸道感染服用复方新诺明0.2g,半小时后出现呼吸困难,咳嗽、咯痰加重,烦躁,不能平卧,吸气时胸骨上窝凹陷明显。语言清晰,唇及指端发绀,无皮疹,双肺满布哮鸣音。经口服强的松等后13小时哮喘症状完全缓解。4天后又试服复方新诺 In recent years, drug-induced bronchial asthma day by clinicians attention. Currently known drugs are more common: β-blockers, antipyretic analgesics, aerosol inhalation agents (isoproterenol, polymyxin B, pituitary extract inhalers, acetylcysteine Acid, disodium cromoglycate) and other drugs (pilocarpine, cholinergic acid and neostigmine). However, cotrimoxazole induced asthma is rare, a report is as follows. Patient girl, 4 years old. Recurrent upper respiratory tract infections in the past year, each taking cotrimoxazole treatment. On May 17, 1985 suffering from respiratory tract infection taking cotrimoxazole 0.2g, half an hour later, dyspnea, cough, expectoration increased, irritability, can not be supine, suprasternal supine socket depression. Clear language, lips and fingers cyanosis, no rash, lungs covered with wheeze. After oral prednisone and other symptoms completely relieved 13 hours after asthma. 4 days later try new compound Connaught