从60年代开始,人们就发现在血小板上除了含有组织相容性抗原(HLA)等共同抗原外,还含有仅存在于血小板膜糖蛋白上的特异性抗原——人类血小板共同抗原(HPA),并对其进行了详细的鉴定和分型。自从1957年Monlinier发现第一个血小板特异性抗体,并检测到血小板特异性抗原以来,在很长一段时间内,血小板特异性抗原是通过血清学方法检测其相应抗体而发现的。到1988年为止,相继发现了PLA、PLE、Ko、Bak、 Since the 1960s, it has been found that platelets contain, in addition to common antigens such as histocompatibility antigens (HLA), specific antigens such as human platelet common antigen (HPA) that are present only on platelet membrane glycoproteins, And its detailed identification and classification. Since Monlinier discovered the first platelet-specific antibody in 1957 and detected platelet-specific antigens, for a long time, platelet-specific antigens were detected by serological detection of their corresponding antibodies. Until 1988, one after another found PLA, PLE, Ko, Bak,